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MODIFIED STARCH DERIVATIVE-BASED MATRIX FOR COLON TARGETING
专利权人:
Olaf Haeusler
发明人:
Olaf Haeusler,Marie-Helene Degrave,Daniel Wils,Stefanie Krenzlin,Juergen Siepmann
申请号:
US13880158
公开号:
US20130202691A1
申请日:
2011.10.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A controlled-release oral pharmaceutical composition of at least an active agent, including: a) a lipophilic matrix consisting of lipophilic compounds and/or amphiphilic compounds and b) an hydrophilic matrix, wherein the hydrophilic matrix includes at least an indigestible polysaccharide, the active ingredient being dispersed in the lipophilic and/or the hydrophilic matrix.The present invention also relates to a process for the preparation of such a pharmaceutical composition.
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