Pharmaceutical composition for protecting liver function comprising arazyme as an active ingredient

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专利权人:

インセクト;リミティッド;インセクト バイオテック カンパニー, リミティッド;カンパニー，;バイオテック

发明人:

パク ホ－ヨン,ソン クワン－ヒー,シン ドン－ハ,ジョン キュ－シク,パク ホ-ヨン,ソン クワン-ヒー,シン ドン-ハ,ジョン キュ-シク

申请号：

JP2009543907

公开号：

JP4954295B2

申请日:

2006.12.28

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

The present invention relates to a pharmaceutical composition for the prevention of liver dysfunction which contains arazyme as an active ingredient, more precisely a pharmaceutical composition for the prevention of liver dysfunction which contains arazyme produced by Aranicola proteolyticus. The arazyme of the present invention inhibits apoptosis in injured liver cells, increases SMP30 expression, inhibits P-smad3 expression and protects liver by inhibiting liver injury around central vein region. Therefore, the arazyme of the invention can be effectively used as a pharmaceutical composition for the prevention of liver dysfunction.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/