Peptides that activate bombesin-like peptide receptors and uses thereof

• 收藏
• 分享

专利权人:

独立行政法人産業技術総合研究所

发明人:

諏訪 牧子,広川 貴次,向井 秀仁

申请号：

JP2006038503

公开号：

JP5030078B2

申请日:

2006.02.15

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

The structures of a plurality of peptide ligands, each having a minimum activity unit which is believed to activate BRS-3, are predicted from the human genome sequence. Next, some peptides each having the minimum activity unit are chemically synthesized based on the predicted peptide structures, and the BRS-3 activation ability of the synthesized peptides are then examined. As a result, it is found that a peptide having the following amino acid sequence: Leu-Trp-Ala-Cys-Gly-Ser-Phe-Met (SEQ ID NO:3) can activate BRS-3 in a selective manner.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/