Che Serguera,Francois Lachapelle,Noelle Dufour,Muhammad Qamar Saeed
申请号:
US15022722
公开号:
US20160230190A1
申请日:
2014.09.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a lentiviral vector wherein the expressed integrase protein comprises at least one point mutation consisting of the substitution of the aspartic acid residue at position 167 by an amino acid selected from the group consisting of histidine, arginine and lysine.