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Bile acid-basic amino acid conjugates and uses thereof
专利权人:
发明人:
Oren Tirosh,Ira Voloshin,Shlomo Sasson,Michal Obercyger,Zecharia Madar
申请号:
US14895723
公开号:
US09884066B2
申请日:
2014.06.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Compositions and methods for treating diseases or disorders associated with the metabolic syndrome using conjugates of bile acids with basic amino acids or a decarboxylated amino acid such as agmatine are provided. Further provided are bile acid-basic amino acid conjugates including chenodeoxycholic acid with an amino acid selected from arginine, lysine, histidine, ornithine or a decarboxylated amino acid such as agmatine.
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