Alexander Teslenko,Dieter Gulik,Friedrich Von Hahn
申请号：
US13821428
公开号：
US09943671B2
申请日:
2011.09.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to an application system for the transepidermal surface administration of medications, said system comprising a container (1) accommodating a sprayable, active agent-containing composition, a propellant gas source (3) for pressurized gas consisting of at least 25% v/v of oxygen, and a spraying device (2), wherein container (1), propellant gas source (3), and spraying device (2) are flow-connected with each other in such a manner that the propellant gas atomizes the sprayable composition and, when the spraying device (2) is actuated, forces it out of the spraying device (2), with the composition being forced out of the spraying device (2) in the form of a conical spray jet at an exit velocity of ≥100 m/s. With the help of the inventive application system active agents can be effectively administered via the skin without causing injury to the skin. As a result of the high exit velocity the penetration rate is especially favorable even when larger molecules are introduced.
