Warren Chew;Gloria Cheal;Mannching Sherry Ku;Anthony F. Hadfield;Mahmoud Mirmehrabi;Qinghong Lu
发明人:
Qinghong Lu,Mannching Sherry Ku,Warren Chew,Gloria Cheal,Anthony F. Hadfield,Mahmoud Mirmehrabi
申请号：
US13441168
公开号：
US20120289545A1
申请日:
2012.04.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to maleate salt forms of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide, methods of preparing crystalline maleate salt forms, the associated compounds, and pharmaceutical compositions containing the same. The maleate salts are useful in treating cancers, particularly those affected by kinases of the epidermal growth factor receptor family.
