PREPARATION OF MALEATE SALT OF NERATININB AND ITS USE
- 专利权人:
- 发明人:
- 申请号：
- HK13107441.5
- 公开号：
- HK1180310A
- 申请日:
- 2013.06.25
- 申请国别(地区):
- HK
- 年份:
- 2013
- 代理人:
- 摘要：
- The present invention relates to maleate salt forms of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide, methods of preparing crystalline maleate salt forms, the associated compounds, and pharmaceutical compositions containing the same. The maleate salts are useful in treating cancers, particularly those affected by kinases of the epidermal growth factor receptor family.
- 来源网站：
- 中国工程科技知识中心
相关发明人
相关专利
- מלחי מאלאט של (e) – n – {4 – [3 – כלורו – 4 – 4 (2 – פירידינילמתוקסי) אנילינו] – 3 – ציאנו – 7 – אתוקסי – 6 – קווינוליניל} – 4 (דימתילאמינו) – 2 – בוטנאמיד וצורות קריסטליות שלהם
- Maleate salts of (E)-N-{4[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
- Maleate Salts of (E)-N--4-(Dimethylamino)-2-Butenamide and Crystalline Forms Thereof
- MALEATE SALTS OF (E)-N-{4-[3-CHLORO-4-(2-PYRIDINYLMETHOXY)ANILINO]-3-CYANO-7-ETHOXY QUINOLINYL}-4-(DIMETHYLAMINO)-2-BUTENAMIDE AND CRYSTALLINE FORMS THEREOF
- MALEATE SALTS OF (E)-N-{4-[3-CHLORO-4-(2-PYRIDINYLMETHOXY)ANILINO]-3-CYANO-7-ETHOXY-6-QUINOLINYL}-4-(DIMETHYLAMINO)-2-BUTENAMIDE AND CRYSTALLINE FORMS THEREOF
