Martin Michels,Markus Follmann,Alexandros Vakalopoulos,Katja Zimmermann,Nicole Teusch,Mario Lobell,Karen Engel
申请号:
US13500470
公开号:
US20120270905A1
申请日:
2010.10.01
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to novel fluorinated 2,6-dialkyl-3,5-dicyano-4-(1H-indazol-5-yl)-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders.