Alexandros Vakalopoulos;Nicole Teusch;Mario Lobell;Katja Zimmermann;Martin Michels;Karen Engel
发明人:
Alexandros Vakalopoulos,Martin Michels,Katja Zimmermann,Nicole Teusch,Mario Lobell,Karen Engel
申请号：
US13509047
公开号：
US09018234B2
申请日:
2010.11.08
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to novel, fluoro-substituted 2-aryl-3,5-dicyano-4-(1H-indazol-5-yl)-6-methyl-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly Cancer and other proliferative disorders.
