PROBLEM TO BE SOLVED: To provide a pharmaceutical composition in which digestion trouble caused by loxoprofen is reduced or suppressed.SOLUTION: The pharmaceutical composition includes following components (A), (B) and (C): (A) loxoprofen or its salt； (B) tranexamic acid or its salt； and (C) one or at least two selected from a group consisting of ephedrines, dextromethorphan or its salt, tipepidine or its salt, codeines, chlorpheniramine or its salt, clemastine or its salt, bromhexine or its salt, ambroxol or its salt, xanthine derivative and guaifenesin.
