DUKSUNG WOMEN&primeS UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
LEE, JAE INKR,이재인
申请号：
KR1020130022980
公开号：
KR1020140110161A
申请日:
2013.03.04
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
A method for preparing heterocyclic derivatives of thioflavones according to the present invention is characterized by comprising a step of preparing heterocyclic derivatives of thioflavones of material 5 from material 1 below, as shown in reaction formula 1 below: (in reaction formula 1, X is any one selected from the group consisting of 2-thienyl. 3-Br(a), 3-thienyl. 2-Br(b), 3-pyridyl. 2-Cl(c), and 3-quinolyl. 2-Cl(d) and R is any one selected from the group consisting of C_6H_6(e), 3-Cl-C_6H_4(f), 4-CH_3-C_6H_4(g), 4-CH_3O-C_6H_4(h), 3,5-(CH_3O)_2-C_6H_3(i), 3-thienyl(j), and 3-pyridyl(f)).COPYRIGHT KIPO 2014본 발명에 따른 싸이오플라본의 헤테로고리 유도체의 제조 방법은 하기 반응식 1과 같이, 하기 물질 1로부터 물질 5의 싸이오플라본의 헤테로고리 유도체를 제조하는 단계를 포함하는 것을 특징으로 한다.<반응식 1>(상기 반응식 1에서 X는 2-thienyl. 3-Br(a), 3-thienyl. 2-Br(b), 3-pyridyl. 2-Cl(c), 및 3-quinolyl. 2-Cl(d)를 포함하는 군 중 어느 하나로 선택되고, 상기 R은 C6H6(e), 3-Cl-C6H4(f), 4-CH3-C6H4(g), 4-CH3O-C6H4(h), 3,5-(CH3O)2-C6H3(i), 3-thienyl(j), 및 3-pyridyl(f)을 포함하는 군 중 어느 하나로 선택된다)
