TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄTSMEDIZIN DER JOHANNES GUTEN-BERG-UNIVER;BIONTECH AG
发明人:
Ugur Sahin,Claudia Paret,Kirsten Vormbrock,Christian Bender,Jan Diekmann
申请号：
US14647577
公开号：
US20160058853A1
申请日:
2013.11.26
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to a patient-specific tumor treatment targeting individual expression patterns of tumor antigens, in particular shared tumor antigens, and individual tumor mutations. In one aspect, the present invention relates to a method for preventing or treating cancer in a patient comprising the steps of: (i) inducing a first immune response against one or more tumor antigens in the patient, and (ii) inducing a second immune response against one or more tumor antigens in the patient wherein the second immune response is specific for cancer specific somatic mutations present in cancer cells of the patient.
