BioNTech RNA Pharmaceuticals GmbH;TRON - Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Universitat Mainz Gemeinnutzige GmbH
发明人:
Sahin, Ugur,Paret, Claudia,Vormbrock, Kirsten,Bender, Christian,Diekmann, Jan
申请号：
AU2013351542
公开号：
AU2013351542A1
申请日:
2013.11.26
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The present invention relates to a patient-specific tumor treatment targeting individual expression patterns of tumor antigens, in particular shared tumor antigens, and individual tumor mutations. In one aspect, the present invention relates to a method for preventing or treating cancer in a patient comprising the steps of: (i) inducing a first immune response against one or more tumor antigens in the patient, and (ii) inducing a second immune response against one or more tumor antigens in the patient wherein the second immune response is specific for cancer specific somatic mutations present in cancer cells of the patient.
