BIONTECH RNA PHARMACEUTICALS GMBH;TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ GEMEINNÜTZIGE GMBH
发明人:
Sahin, Ugur,Paret, Claudia,Vormbrock, Kirsten,Bender, Christian,Diekmann, Jan
申请号：
AU2018256508
公开号：
AU2018256508A1
申请日:
2018.10.30
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention relates to a patient-specific tumour treatment targeting individual expression patterns of tumour antigens, in particular shared tumour antigens, and individual tumour mutations. In one aspect, the present invention relates to a method for preventing or treating cancer in a patient comprising the steps of: (i) inducing a first immune response against one or more tumour antigens in the patient, and (ii) inducing a second immune response against one or more tumour antigens in the patient wherein the second immune response is specific for cancer specific somatic mutations present in cancer cells of the patient.
