Composition (A) containing a cyclic depsipeptide (I) (optionally together with other active agents) additionally contains at least one solvent (II) and is formulated for topical administration to animals. An independent claim is included for the preparation of (A), by mixing (I) with (II) and optionally further additives. - ACTIVITY : Antiparasitic； anthelmintic. A solution of 5 wt.% depsipeptide (unspecified) in 66.5 wt. % isopropylidene glycerol and 28.5 wt. % benzyl alcohol gave 100% control of Toxocara canis and Ancylostoma caninum in dogs and Toxocara cati in cats within 2-4 days at a depsipeptide dosage of 5 mg/kg. - MECHANISM OF ACTION : None given.
