JOCHEN KALBE,MICHAEL TRAEUBEL,GEORG VON SAMSON-HIMMELST JERNA,ACHIM HARDER,MICHAEL STEGEMANN,NORBERT MENCKE
申请号：
BR0108562
公开号：
BR0108562B1
申请日:
2001.02.09
申请国别(地区):
BR
年份:
2013
代理人:
摘要：
Composition (A) containing a cyclic depsipeptide (I) (optionally together with other active agents) additionally contains at least one solvent (II) and is formulated for topical administration to animals. An independent claim is included for the preparation of (A), by mixing (I) with (II) and optionally further additives. - ACTIVITY : Antiparasitic； anthelmintic. A solution of 5 wt.% depsipeptide (unspecified) in 66.5 wt. % isopropylidene glycerol and 28.5 wt. % benzyl alcohol gave 100% control of Toxocara canis and Ancylostoma caninum in dogs and Toxocara cati in cats within 2-4 days at a depsipeptide dosage of 5 mg/kg. - MECHANISM OF ACTION : None given.
