#$%^&*AU2019229369A120191003.pdf#####67 Abstract An inhaler device for delivery of at least one active substance to an inhaling user comprises a first conduit for conducting airflow to an opening from which the user inhales； a valve positioned and configured to affect flow of ambient air into the first conduit； a controller configured to control release of the at least one active substance to be carried by the airflow to the inhaling user. The controller is further configured to control the valve to generate a pattern of airflow and active substance delivery modulations. The pattern includes and there is also a method disclosed which includes: (a) delivering the active substance via the airflow followed by substantially stopping active substance delivery and reducing a total rate of airflow to the user for an intermediate period, and then (b) increasing the airflow without resuming active substance delivery to a rate or volume sufficient to be sensed by the inhaling user.Select a profile of flow through the drug 122 Dynamically control additional air flow according to an estimated flow through the drug and the selected flow profile FIG. 1A
