Smaill, Jeffrey Bruce,Patterson, Adam Vorn,Ashoorzadeh, Amir,Guise, Christopher Paul,Mowday, Alexandra Marie,Ackerley, David Francis,Williams, Elsie May,Copp, Janine Naomi
申请号：
AU2013306514
公开号：
AU2013306514B2
申请日:
2013.08.22
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The invention relates to compounds of use as targeted cytotoxic agents and methods of use thereof. In particular, the invention relates to prodrugs that are substantially resistant to human AKR1C3 enzyme metabolism, methods of cell ablation using said compounds and methods of treatment of cancer and other hyperproliferative disorders using said compounds.
