ANTI-TRANSTHYRETIN HUMAN ANTIBODY

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专利权人:

The Chemo-Sero-Therapeutic Research Institute

发明人:

TORIKAI, Masaharu,HOSOI, Akihiko,TAKEO, Tomoyo,UENO, Masayo,SOEJIMA, Kenji,NAKASHIMA, Toshihiro,ANDO, Yukio,JONO, Hirofumi,SU, Yu,MIZUGUCHI, Mineyuki

申请号：

EP15743541

公开号：

EP3101132A4

申请日:

2015.01.23

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

A human antibody which comprises a complementarity determining region of an H chain consisting of the amino acid sequence as shown in SEQ ID NOs: 1 to 3 and a complementarity determining region of an L chain consisting of the amino acid sequence as shown in SEQ ID NOs: 4 to 6. The human antibody of the present invention has the activity to specifically bind to transthyretin (TTR) with structural change and the activity to inhibit fibrillization of TTR and is a human antibody suitable for application to human body.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/