Anti-transthyretin human antibody

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专利权人:

LTD.;KM BIOLOGICS CO.

发明人:

Masaharu Torikai,Akihiko Hosoi,Tomoyo Takeo,Masayo Ueno,Kenji Soejima,Toshihiro Nakashima,Yukio Ando,Hirofumi Jono,Yu Su,Mineyuki Mizuguchi

申请号：

US15114545

公开号：

US10597440B2

申请日:

2015.01.23

申请国别(地区):

US

年份:

2020

代理人:

摘要：

A human antibody which comprises a complementarity determining region of an H chain consisting of the amino acid sequence as shown in SEQ ID NOs: 1 to 3 and a complementarity determining region of an L chain consisting of the amino acid sequence as shown in SEQ ID NOs: 4 to 6. The human antibody of the present invention has the activity to specifically bind to transthyretin (TTR) with structural change and the activity to inhibit fibrillization of TTR and is a human antibody suitable for application to human body.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/