Disclosed is a device, a kit, and a method of use thereof, for self-administration and collection of cervical cell tissue samples such as for Pap smear testing. The device comprises an insertion tube (20), an elongated cervical alignment tool (40) and an elongated cellular sampling tool (60). The insertion tube comprises a passage containing the cervical aligning tool therein. The cervical alignment tool comprises with an aligning probe (48) and a handle (46), separated with a body (50) therebetween. The cellular sampling tool comprises a cellular adhesion surface (68) and a handle (66). The cervical aligning tool handle is disposed outside the insertion tube passage and is moveable between a first position, wherein the probe is within the passage, and a second position, wherein the probe extends from the passage to engage a cervical fornix of a patient. The elongated cellular sampling tool is shaped for insertion within the passage, upon a portion of the aligning tool and within the aligning tool handle. The handle of the cellular sampling tool extends from the passage and is releasably movable between a first position, for insertion, and a second position, for sampling. The sampling tool can be rotatably engaged with the alignment tool, such that the sampling tool may be rotated during sample collecting. The aligning probe and cellular adhesion surface can be selectively movable relative to the insertion tube to improve accuracy of the testing and user safety.
