MURINE MODEL OF INFLAMMATION WITH IL33 N-TERMINAL DOMAIN DELETION

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专利权人:

发明人:

申请号：

EP11776153.6

公开号：

EP2632250A1

申请日:

2011.10.26

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates to a non-human animal deficient in the N-terminal domain of the IL-33 gene. Also provided herein is the use of said non-human animal as an in vivo model of inflammatory diseases, especially with regard to screening methods for anti-inflammatory compounds, and methods for evaluating and optimising the pharmacological properties of a given anti-inflammatory compound.

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