A method of imaging a region containing an internal target tissue of a subject, comprising: inserting an intracorporeal ultrasound device to the subject positioning an extracorporeal ultrasound device opposite to said intracorporeal ultrasound device, such that at least a portion of the region is interposed between said intracorporeal ultrasound device and said extracorporeal ultrasound device using said intracorporeal ultrasound device and said extracorporeal ultrasound device to transmit ultrasonic radiation through the region scanning the region using at least one of said intracorporeal ultrasound device and said extracorporeal ultrasound device and analyzing said ultrasonic radiation so as to generate an image of the region by transmission ultrasound computerized tomography (TUCT).
