DILARA MCCAULEY,SHARON SCHECHTER,SHARON SHACHAM,VINCENT P. SANDANAYAKA
申请号：
BR112014001934
公开号：
BR112014001934A2
申请日:
2012.07.26
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I: or a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity.
