Vincent P. Sandanayaka,Sharon Shacham,Dilara McCauley,Sharon Shechter
申请号：
US14219638
公开号：
US08999996B2
申请日:
2014.03.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I:or a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity.
