KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
LIU, KWANG HYEONKR,류광현,SHON, JONG CHEOLKR,손종철,WU ZHEXUECN,오철학,LIU, KWANG HYEON,SHON, JONG CHEOL,WU ZHEXUE
申请号:
KR1020170060779
公开号:
KR1019088530000B1
申请日:
2017.05.17
申请国别(地区):
KR
年份:
2018
代理人:
摘要:
The present invention relates to a composition for inhibiting cytochrome P450 enzyme containing acetylshikonin as an active ingredient, and when the composition is used, the activity of the cytochrome P450 enzyme selected from a group consisting of cytochrome P450 1A2, 2A6, 2B6, 2D6, 2C8, 2C9, 2C19, 3A, 2E1 and 2J2 can be remarkably inhibited.COPYRIGHT KIPO 2018본 발명은 아세틸시코닌을 유효성분으로 함유하는 시토크롬 P450 억제용 조성물로, 상기 조성물을 이용하면 시토크롬 P450 1A2, 2A6, 2B6, 2D6, 2C8, 2C9, 2C19, 3A, 2E1 및 2J2로 이루어진 군에서 선택되는 시토크롬 P450 동효소의 활성을 현저하게 저해할 수 있다.