Arasappan, Ashok,Cox, Jason M.,Debenham, John S.,Guo, Zhuyan,He, Jiafang,Hussain, Zahid,Lai, Zhong,Li, Derun,Meng, Dongfang,Raghavan, Subharekha,Tyagarajan, Sriram
申请号：
AU2018281131
公开号：
AU2018281131A1
申请日:
2018.06.06
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
The present invention is directed to pyrazolopyrimidine compounds which may be useful as therapeutic agents for the treatment of disorders associated with phosphodiesterase 9 (PDE9). The present invention also relates to the use of such compounds for treating cardiovascular and cerebrovascular diseases, such as hypertension, chronic kidney disease and heart failure, and neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
