ARASAPPAN, ASHOK,COX, JASON M.,DEBENHAM, JOHN S.,GUO, ZHUYAN,HE, JIAFANG,HUSSAIN, ZAHID,LAI, ZHONG,LI, DERUN,MENG, DONGFANG,RAGHAVAN, SUBHAREKHA,TYAGARAJAN, SRIRAM
申请号：
CA3064938
公开号：
CA3064938A1
申请日:
2018.06.06
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention is directed to pyrazolopyrimidme compounds which may beuseful as therapeutic agents for thetreatment of disorders associated with phosphodiesterase 9 (PDE9) The presentinvention also relates to the use of such compounds fortreating cardiovascular and cerebrovascular diseases, such as hypertension,chronic kidney disease and heart failure, and neurologicaland psychiatric disorders, such as schizophrenia, psychosis or Huntington'sdisease, and those associated with striatal hypofunction orbasal ganglia dysfunction
