The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, pharmaceutical preparations or pharmaceutical compositions thereof, and their use in the treatment of pain, inflammatory diseases, neuropathy, skin diseases, lung diseases and cough, and the inhibition of transient receptor potential A1 ion channel (TRPA1).本發明涉及式(I)的化合物，或其藥學上可接受的鹽、藥物製劑或藥物組合物，以及它們治療疼痛、炎性疾病、神經病、皮膚病、肺部疾病和咳嗽，以及抑制瞬時受體電位A1離子通道(TRPA1)的用途。
