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Small-molecule-targeted protein degradation
专利权人:
Brandeis University
发明人:
Hedstrom, Lizbeth K.,Long, Marcus,Gollapalli, Deviprasad R.
申请号:
AU2011272860
公开号:
AU2011272860A1
申请日:
2011.06.30
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Certain aspects of the invention relate to compounds, compositions and methods that are useful for treating or preventing a disease in a subject by enhancing the degradation of a protein. In other aspects, said compounds can be useful research tools for investigating protein degradation. In other aspects, said compounds are useful research tools for investigating protein function. In certain embodiments, the degraded protein is implicated in a disease or disorder whose pathology is related at least in part to the excessive expression of the protein or the expression of a mutant form of the protein.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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