PATZAK, ULRICH,COLLEDGE, JEFFREY,OUATAS, TAOUFIK,OLTHOFF, MARGARETHA,PROFITLICH, THOMAS ALFRED
申请号：
NZ59297109
公开号：
NZ592971A
申请日:
2009.12.03
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
592971 Disclosed is a pharmaceutical composition in a solid dosage form for oral administration, the composition comprising bendamustine or a pharmaceutically acceptable ester, salt or solvate thereof as an active ingredient, and at least one pharmaceutically acceptable excipient, which is a pharmaceutically acceptable saccharide selected from the group consisting of one or more of a monosaccharide, a disaccharide, an oligosaccharide, a cyclic oligosaccharide, a polysaccharide and a saccharide alcohol, wherein the ratio by weight of the active ingredient to the saccharide excipient(s) is in the range of 1:1-10, and wherein the pharmaceutical composition is in the form of a tablet, a granulate, or a pill. Also disclosed is the use of the composition in the manufacture of a medicament for the treatment of a medical condition which is selected from chronic lymphocytic leukemia, acute lymphocytic leukaemia, chronic myelocytic leukaemia acute myelocytic leukaemia, Hodgkins disease, non-Hodgkins lymphoma, multiple myeloma, breast cancer, ovary cancer, small cell lung cancer, non-small cell lung cancer, and an autoimmune disease.
