Gregory T. WENT,Timothy J. FULTZ,Sangita GHOSH,Natalie MCCLURE
申请号：
US16409554
公开号：
US20190262285A1
申请日:
2019.05.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Provided herein are oral pharmaceutical compositions comprising amantadine, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient, and which have a low level of organic solvent. Provided are also methods of orally administrating a composition comprising amantadine, or a pharmaceutically acceptable salt thereof, to a subject, which has reduced gastrointestinal side effects or sleep disturbances. Further provided are extended release oral compositions comprising amantadine, or a pharmaceutically acceptable salt thereof, that are suitable for once daily administration.
