SB PHARMCO PUERTO RICO INC.;NEUROCRINE BIOSCIENCES INC.
发明人:
LANIER, MARION,LUO, ZHIYONG,MOORJANI, MANISHA,TELLEW, JOHN EDWARD,WILLIAMS, JOHN P.,ZHANG, XIAOHU
申请号：
CA2584567
公开号：
CA2584567C
申请日:
2005.10.19
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
CRF receptor antagonists are disclosed which may have utility in the treatmentof a variety of disorders, including the treatment of disorders manifestinghypersecretion of CRF in mammals. The CRF receptor antagonists of thisinvention have the following structure: (I)； and pharmaceutically acceptablesalts, esters, solvates, stereoisomers and prodrugs thereof, wherein R1, R2a,R2b, Y, Het, n, o, R6, Ar and R7 are as defined herein. Compositionscontaining a CRF receptor antagonist in combination with a pharmaceuticallyacceptable carrier are also disclosed, as well as methods for use of the same.
