CHEN CHEN,ZHIQIANG GUO,YUN-FEI ZHU,FABIO C. TUCCI,TIMOTHY D. GROSS,MARTIN ROWBOTTOM,R. SCOTT STRUTHERS
申请号：
PT01910362
公开号：
PT1255738E
申请日:
2001.01.25
申请国别(地区):
PT
年份:
2012
代理人:
摘要：
GnRH receptor antagonists are disclosed that have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein A, Q, R1, R2, R3a, R3b, R4, R5, R6 and n are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
