NOUVEAUX COMPOSES AYANT UNE ACTIVITE ANTI-ALLODYNIQUE ET ANTIHYPERALGESIQUE

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专利权人:

CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI INSTM;UNIVERSITA' DEGLI STUDI DI FIRENZE

发明人:

NATIVI, CRISTINA,GHELARDINI, CARLA,LA MARCA, GIANCARLO

申请号：

CA2940361

公开号：

CA2940361A1

申请日:

2014.02.27

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The present invention relates to molecules of formula (I) where R1 = -SO3H, -PO3H, -PO2(OH)2, -OPO2H2, -NHSO3H, -S (N=H)Me, SH, SR o guanidyl； R = C1-4 alkyl, phenyl or 5 or 6 membered aromatic nitrogen heterocycles； n = 1, 2, 3, 4 o 5； X = C=0, C(OH)H, C(OAIk)H, C=S, CH2； Alk = C1-6 alkyl linear, branched or cyclic, optionally hydroxylated or polyhydroxylated； their preparation and use as analgesics and in the treatment of pain induced by chemotherapies.

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