CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI;UNIVERSITA DEGLI STUDI DI FIRENZE
发明人:
Cristina NATIVI,Carla GHELARDINI,Giancarlo LA MARCA
申请号：
US15121649
公开号：
US20160362402A1
申请日:
2014.02.27
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to molecules of formula (I) where R1=—SO3H, —PO3H, —PO2(OH)2, —OPO2H2, —NHSO3H, —S(N═H)Me, SH, SR or guanidyl； R═C1-4 alkyl, phenyl or 5 or 6 membered aromatic nitrogen heterocycles； n=1, 2, 3, 4 or 5； X═C=0, C(OH)H, C(OAlk)H, C═S, CH2； Alk=C1-6 alkyl linear, branched or cyclic, optionally hydroxylated or polyhydroxylated； their preparation and use as analgesics and in the treatment of pain induced by chemotherapies.
