Meerpoel, Lieven,Backx, Leo Jacobus Jozef,Busscher, Guuske Frederike,Ten Holte, Peter
申请号:
AU2007310927
公开号:
AU2007310927B2
申请日:
2007.10.22
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention is concerned with novel tetrahydro-naphthalene-1-carboxylicacid derivatives having apoB secretion/MTP inhibiting activity and concomitantlipid lowering activity. The invention further relates to methods for preparingsuch compounds, pharmaceutical compositions comprising said compounds aswell as the use of said compounds as a medicine for the treatment of atherosclerosis,pancreatitis, obesity, hypertriglyceridemia, hypercholesterolemia, hyperlipidemia,diabetes and type II diabetes. Formula (I).