PURPOSE: A fumigant for preventing honey bee is provided to standardize organic acid and plant essential oil as a main ingredient and to enhance prevention efficiency. CONSTITUTION: A fumigant for preventing honey bee contains organic acid and fumigation catalyst. The organic acid is oxalic acid, acetic acid, lactic acid, succinic acid, tartaric acid, or malic acid. The fumigation catalyst is a beeswax existing at least one side of the fumigant. The fumigant further comprises fumigant relieving agent of crystal cellulose or hydroxy propylmethyl cellulose. The fumigant relieving agent is 20-50 weight parts based on 100 weight parts of total fumigant.본 발명은 안전하고 효과적인 꿀벌 병해충 방제를 위해 유기산과 식물정유를 주성분으로 규격화된 친환경 훈증 정제를 개발함으로써 양봉가가 사용하기에 간편하고 안전하며, 방제 효율이 높은 꿀벌 병해충 방제 효과를 얻을 수 있다.