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TREATMENT OF OSTEOPOROSIS
专利权人:
ХАОМАМЕДИКА ЛИМИТЕД (GB)
发明人:
ХОДЖЕС Стивен (GB),СОПЕР Робин (GB)
申请号:
RU2012130936/04
公开号:
RU2012130936A
申请日:
2010.12.22
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. The use of the compounds of formula (I) where: R represents hydrogen, halogen, cyano, trifluoromethyl, nitro, -OR, SR, SOR, -SOR, -SONRR, -NRR, -NRCOR, -NRCOR, -COR, -COR, —CONRR or a hydrocarbon group comprising a straight chain group, a branched or cyclic group each containing up to 18 carbon atoms, or a heterocyclic group containing up to 18 carbon atoms and at least one heteroatom; R is independently in each case , hydrogen, halogen, cyano, trifluoromethyl, nitro, -OR, SR, SOR, -SOR, -SONRR, -NRR, -NRCOR, -NRCOR, -COR, -COR, -CONRR or a hydrocarbon group comprising a straight chain group, a branched or cyclic group each containing up to 18 carbon atoms, or a heterocyclic group containing up to 18 carbon atoms and at least one heteroatom; R is a hydrocarbon group including a straight chain group a chain, branched or cyclic group, each of which contains up to 18 carbon atoms, and substituted by at least one residue including a -COR substituent; where R and R are not independently, in each case, a hydrogen or hydrocarbon group comprising a straight chain group, a branched or cyclic group, each of which contains up to 18 carbon atoms, or a heterocyclic group containing up to 18 carbon atoms and at least one heteroatom; and n is 0, 1, 2, 3, or 4; or a pharmaceutically acceptable solvate thereof or, more preferably, a salt or prodrug thereof for the treatment of osteoporosis and / or osteopenia. 2. The use according to claim 1, in which R or R is hydrogen, halogen, cyano, trif1. Применение соединения формулы (I)где:Rпредставляет собой водород, галоген, циано, трифторметил, нитро, -OR, SR, SOR, -SOR, -SONRR, -NRR, -NRCOR, -NRCOR, -COR, -COR, -CONRRили углеводородную группу, включающую группу с неразветвленной цепью, разветвленную или циклическую группу, каждая из которых содержит вплоть до 18 атомов углерода, или гетероциклическую группу, содержащую вплоть до 18 атомов углерода и по меньшей мере один гетероатом;Rпредставляет собой, независимо в каждом случае, водоро
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