Refers to compounds (Derivatives of 1 - phenyl - 2 - pyridin-4-yl) ethyl Esters of benzoic acid of formula (i) and (-) enantiomer where n is 0 OR 1 R1 and R2 are each alkyl (C1 - C6) optionally substituted by Halogen, or hnso2r4 OR3, where R3 is alkyl (C1 - C6) optionally replaced with Hal Ogeno or cycloalkyl (C3 - C7) R4 is alkyl (c1-c4) optionally substituted by Halogen.Preferred compounds are: 1 - (S) - (Cyclopropylmethoxy Difluoromethoxy - 3 - 4 - phenyl) - 2 - (3,5 - Dichloro pyridin-4-yl) - acid ethyl ester Cyclopropylmethoxy - 3 - 4 - 1 - metanosulfonilamino - benzoic acid (S) - 3 - (Cyclopropylmethoxy Difluoromethoxy - 4 - - phenyl) - 2 - (3,5 - Dichloro - 1 - Oxy pyridin-4-yl) - 3 - ciclopropi acid ethyl ester Lmetoxi - 4 - metanosulfonilamino - benzoic acid among others.It also refers to a process of Preparation and to a Pharmaceutical composition that contains formoterol or carmoterol. These compounds are inhibitors of the Enzyme phosphodiesterase 4 (PDE4) being useful in the treatment of Asthma, chronic obstructive pulmonary diseaseSE REFIERE A COMPUESTOS DERIVADOS DE (1-FENIL-2-PIRIDIN-4-IL)ETIL ESTERES DEL ACIDO BENZOICO DE FORMULA (I) COMO (-) ENANTIOMERO DONDE n ES 0 O 1 R1 Y R2 SON CADA UNO ALQUILO(C1-C6) OPCIONALMENTE SUSTITUIDO CON HALOGENO, OR3 O HNSO2R4, EN DONDE R3 ES ALQUILO(C1-C6) OPCIONALMENTE SUSTITUIDO CON HALOGENO O CICLOALQUILO(C3-C7) R4 ES ALQUILO(C1-C4) OPCIONALMENTE SUSTITUIDO CON HALOGENO. SON COMPUESTOS PREFERIDOS: 1-(S)-(3-CICLOPROPILMETOXI-4-DIFLUOROMETOXI-FENIL)-2-(3,5-DICLORO-PIRIDIN-4-IL)-ETIL ESTER DEL ACIDO 3-CICLOPROPILMETOXI-4-METANOSULFONILAMINO-BENZOICO 1-(S)-(3-CICLOPROPILMETOXI-4-DIFLUOROMETOXI-FENIL)-2-(3,5-DICLORO-1-OXI-PIRIDIN-4-IL)-ETIL ESTER DEL ACIDO 3-CICLOPROPILMETOXI-4-METANOSULFONILAMINO-BENZOICO ENTRE OTROS. TAMBIEN SE REFIERE A UN PROCESO DE PREPARACION Y A UNA COMPOSICION FARMACEUTICA QUE ADEMAS CONTIENE FORMOTEROL O CARMOTEROL. DICHOS COMPUESTOS SON INHIBIDORES DE LA ENZIMA FOSFODIESTERASA 4 (PDE4) SIENDO
