Koji Masuda,Shiro Kida,Naoki Yoshikawa,Manabu Katou,Terukazu Kato,Mado Nakajima,Eiichi Kojima,Mitsuhiro Yonehara
申请号：
US13516441
公开号：
US08754113B2
申请日:
2010.12.14
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A compound represented by the formula:or its pharmaceutically acceptable salt. Ring A is aromatic carbocycle or aromatic heterocycle, Z is —O— or —S—, R1 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like, R2 and R3 are each independently hydrogen, halogen, hydroxy or the like, R4 is a group represented by the formula: —(CR6R7)n—R8, R6 and R7 are each independently hydrogen, halogen, hydroxy or the like, n is an integer of 0 to 3, R8 is carboxy, cyano, substituted or unsubstituted alkyl or the like, Rx is halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like, and m is an integer of 0 to 3.
