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OXADIAZOLE DERIVATIVE HAVING ENDOTHELIAL LIPASE INHIBITORY ACTIVITY
专利权人:
发明人:
MASUDA KOUJI,KIDA SHIRO,YOSHIKAWA NAOKI,KATOU MANABU,KATO TERUKAZU,NAKAJIMA MADO,KOJIMA EIICHI,YONEHARA MITSUHIRO
申请号:
IN6047/CHENP/2012
公开号:
IN2012CN06047A
申请日:
2012.07.10
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
55123467n8678XProvided is a compound useful as an endothelial lipase inhibitor. The compound is a compound represented by formula (I) a pharmaceutically acceptable salt thereof or a solvate of either. In formula (I) ring A is an aromatic carbocycle or an aromatic heterocycle Z is NR O or S R is a hydrogen atom an (un)substituted alkyl an (un)substituted aryl etc. R is a hydrogen atom a halogen atom hydroxy cyano nitro carboxy an (un)substituted alkyl etc. R and R each independently is a hydrogen atom a halogen atom hydroxy etc. R is a group represented by the formula (CRR) R (wherein R and R each independently is a hydrogen atom a halogen atom hydroxy etc. n is an integer of 0 3 and R is carboxy cyano an (un)substituted alkyl etc.) R is a halogen atom hydroxy cyano nitro carboxy an (un)substituted alkyl etc. and m is an integer of 0 3.
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