人類化之抗因子D抗體及其用途农业专利-农业学术服务平台

发明人:: HUANG, ARTHUR J.,黄　亚瑟Ｊ,黃　亞瑟Ｊ,KELLEY, ROBERT F.,凯力　罗伯特Ｆ,凱力　羅伯特Ｆ,LOWMAN, HENRY,罗门　亨利,羅門　亨利,VAN LOOKEREN CAMPAGNE, MENNO,凡　鲁克恩　迦配恩　曼诺,凡　魯克恩　迦配恩　曼諾,WINTER, CHARLES M.,维特　查理斯Ｍ,維特　查理斯Ｍ,黄亚瑟J,黃亞瑟J,凯力罗伯特F,凱力羅伯特F,罗门亨利,羅門亨利,凡鲁克恩迦配恩曼诺,凡魯克恩迦配恩曼諾,维特查理斯M,維特查理斯M

摘要：: The invention relates to anti-Factor D antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.本發明係關於抗因子D抗體，其核酸及胺基酸序列，含有此等抗體之細胞及載體，及其產生，及其用於製備用於治療與過度或不受控制之補體活化有關之疾病及病症的組合物及藥劑之用途。此等抗體可用於診斷、預防及治療疾病。