人類化之抗因子D抗體及其用途农业专利-农业专业知识服务系统

发明人:: HUANG,ARTHUR J.,黄亚瑟　J,黃亞瑟　J,KELLEY,ROBERT F.,凯力罗伯特　F,凱力羅伯特　F,LOWMAN,HENRY,罗门亨利,羅門亨利,VAN LOOKEREN CAMPAGNE,MENNO,迦配恩曼诺　凡　鲁克恩,迦配恩曼諾　凡　魯克恩,WINTER,CHARLES M.,维特查理斯　M,維特查理斯　M,黄亚瑟 J,黃亞瑟 J,凯力罗伯特 F,凱力羅伯特 F,迦配恩曼诺凡鲁克恩,迦配恩曼諾凡魯克恩,维特查理斯 M,維特查理斯 M

摘要：: The invention relates to anti-Factor D antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease.本發明係關於抗因子D抗體，其核酸及胺基酸序列，含有此等抗體之細胞及載體，及其產生，及其用於製備用於治療與過度或不受控制之補體活化有關之疾病及病症的組合物及藥劑之用途。此等抗體可用於診斷、預防及治療疾病。