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SELECTIVE BINDING OF AGGREGATING PROTEINS
专利权人:
发明人:
LANE AMIN REZA,WILSON STUART MARK,STANLEY CHRISTOPHER J
申请号:
IN2451/DELNP/2004
公开号:
IN254332B
申请日:
2004.08.23
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
Infective aggregating forms of proteins such as PrP, amyloid, and tau are bound selectively in the presence of the normal form protein using a polyionic binding agent such as dextran sulphate or pentosan (anionic), or polyamine compounds such as pDADMAC (cationic) under selective binding conditions including the use of n-lauroylsarcosine at mildly alkaline pH, and may then be assayed.
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