COMPOSES IMIDAZO[1,2-A]PYRIDINE UTILISES COMME INHIBITEURS DES RECEPTEURS A ACTIVITE TYROSINE KINASE

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专利权人:

ARRAY BIOPHARMA INC.

发明人:

ALLEN, SHELLEY,GRESCHUK, JULIE MARIE,KALLAN, NICHOLAS C.,MARMSATER, FREDRIK P.,MUNSON, MARK C.,RIZZI, JAMES P.,ROBINSON, JOHN E.,SCHLACHTER, STEPHEN T.,TOPALOV, GEORGE T.,ZHAO, QIAN,LYSSIKATOS, JOSEPH

申请号：

CA2682981

公开号：

CA2682981C

申请日:

2008.03.27

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

Compounds of Formula I: in which A, B, R1, R1a, R2, R3, R4, R5 R6, R7 and R8 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by class 3 and class 5 receptor tyrosine kinases. Particular compounds of this invention have also been found to be inhibitors of Pim-1.

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http://www.ckcest.cn/home/