Nicholas C. Kallan;John E. Robinson;Fredrik P. Marmsäter;Mark C. Munson;James P. Rizzi;George T. Topalov;Julie Marie Greschuk;Shelley Allen;Joseph P. Lyssikatos;Stephen T. Schlachter;Qian Zhao
发明人:
Shelley Allen,Julie Marie Greschuk,Nicholas C. Kallan,Fredrik P. Marmsäter,Mark C. Munson,James P. Rizzi,John E. Robinson,Stephen T. Schlachter,George T. Topalov,Qian Zhao,Joseph P. Lyssikatos
申请号：
US12593879
公开号：
US08138181B2
申请日:
2008.03.27
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compounds of Formula I: in which A, B, R1, R1a, R2, R3, R4, R5 R6, R7 and R8 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by class 3 and class 5 receptor tyrosine kinases. Particular compounds of this invention have also been found to be inhibitors of Pim-1.
