ALLEN SHELLEY,GRESCHUK JULIE MARIE,KALLAN NICHOLAS C,MUNSON MARK C,RIZZI JAMES P,SCHLACHTER STEPHEN T,TOPALOV GEORGE T,ZHAO QIAN,LYSSIKATOS JOSEPH P,MARMSATER FREDRIK P,ROBINSON JOHN E
申请号:
ZA200907674
公开号:
ZA200907674B
申请日:
2009.11.02
申请国别(地区):
ZA
年份:
2013
代理人:
摘要:
Compounds of Formula I: in which A, B, R1, R1a, R2, R3, R4, R5 R6, R7 and R8 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by class 3 and class 5 receptor tyrosine kinases. Particular compounds of this invention have also been found to be inhibitors of Pim-1.