David Gally;Tom Nathan McNeilly;David George Emslie Smith;Chris Low;Arvind Kumar Mahajan;Stuart W. Naylor
发明人:
David Gally,Tom Nathan McNeilly,David George Emslie Smith,Chris Low,Arvind Kumar Mahajan,Stuart W. Naylor
申请号:
US12738627
公开号:
US09193770B2
申请日:
2008.10.17
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Immunogenic compositions containing Escherichia coli O157:H7 flagella including fusion proteins and methods using the immunogenic compositions are disclosed. Inducing an immune response in an animal to Escherichia coli O157:H7 flagella will result in prevention of colonization by Escherichia coli O157:H7 in the animal or a reduction in the amount of Escherichia coli O157:H7 infecting the animal. The immune composition will prevent or reduce the attachment of Escherichia coli O157:H7 to cells within the animal.